Gene editing has delivered remarkable results against sickle cell disease. Now researchers are working to make these ...

A single infusion of an experimental gene-editing therapy reduced LDL cholesterol in patients with familial ...

For the roughly 30,000 Americans living with hemophilia and thousands more with rare enzyme deficiencies, treatment often means a lifetime of intravenous infusions, sometimes multiple times a week. A ...

Jason is a general assignment reporter, with particular focus on genetic medicine and rare disease. Confidential tips can be sent on Signal at JasonMast.77. Editas Medicine said Tuesday it will ...

Cell therapies could help in the treatment of hereditary diseases, myocardial infarction and hundreds of other diseases. For many blood diseases, new cells can already be transplanted into human ...

When you would like to correct the gene, you have to keep in mind that close to the gene, there are a lot of regulatory elements that are relevant for correct gene expression.-Maria Carmina Castiello, ...

Cell transfection is an important technique for various cell engineering applications, and researchers use various transfection methods for different purposes. Electroporation is among such techniques ...

Researchers led by developmental biologist Kathy Niakan at the University of Cambridge have used base editing in human embryos to learn more about human embryonic development. By deactivating a gene ...

Our cells need to be able to recognize potential invaders as a threat, the key function of the body's innate immune system. Sometimes this process fails, causing the body to react to its own cells, ...

Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, these molecules also play an important role in normal cellular signaling.