Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...
In the past few years, gel electrophoresis of DNA fragments has become an important complement to hybridization and amplification sequencing tools. As variations on PCR, RFLP, mutation sequencing, and ...
Bacteriophages deploy streamlined yet robust strategies to replicate their DNA within host cells. Replication typically initiates at defined viral origins recognised by phage-encoded initiator ...
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