From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

Researchers developed C28, an engineered polymerase that efficiently synthesizes RNA at near-natural speeds with high accuracy. Created through directed evolution, the enzyme also performs reverse ...

DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine.

(Nanowerk Spotlight) Genetic engineering has brought us revolutionary advances in medicine, biotechnology, and our understanding of life itself. However, the precise manipulation of DNA sequences has ...

The origin of SARS-CoV-2 remains unresolved. In a non-peer-reviewed preprint published on bioRxiv on Oct. 20, 2022 three authors present analyses that, according to their interpretation, suggest a ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Scientists have uncovered new DNA-binding proteins from some of the most extreme environments on Earth and shown that they ...

Deep in your muscles, an enzyme called AMPD1 helps turn chemical fuel into usable energy. When it does not work well, muscles tire faster.