Care for patients with cystic fibrosis has undergone transformative changes over the past decade and serves as an example of how an understanding of the functional consequences of a genetic disease ...

The human liver carries out a wealth of vital functions through highly coordinated processes involving multiple cell types. However, when the liver is damaged by pharmaceuticals, cholestasis or ...

ALBUQUERQUE, N.M. (KRQE) – A flaw in the system may be dangerous for people with Cystic Fibrosis. Cystic Fibrosis is when a mutation creates mucus in the lungs, making it hard to breath. Thirty ...

NEW ORLEANS--(BUSINESS WIRE)-- FibroGen, Inc. today announced that administration of investigational therapy FG-3019, a human monoclonal antibody against connective tissue growth factor (CTGF), ...

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its ...

Fibrosis occurs when permanent scar tissue forms during wound healing and can strike almost any of the body’s tissues and organs with devastating consequences. In fact, statistics show that it ...

Liver fibrosis is characterized by the excessive deposition of extracellular matrix, a process primarily driven by activated hepatic stellate cells ...

Many liver diseases share a common characteristic: fibrosis, the progressive accumulation of scarring in the liver tissue.

Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection. "Infected areas of the lung ...

In asymptomatic patients with severe aortic stenosis, higher midwall fibrosis burden is linked to a higher risk for adverse outcomes.