Folate coenzymes are pivotal for one-carbon transfers in nucleotide and amino acid metabolism. Microorganisms synthesise folate de novo, making the pathway an attractive target for antimicrobial and ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

A new international clinical intervention study published in Clinical Nutrition reveals the molecular and transcriptomic mechanisms through which a dietary intervention may beneficially influence gene ...

Thanks to major advances in the field of cancer metabolism during the past two decades, it has become apparent that tumour initiation and progression are not defined only by specific mutations and ...

Just when you thought you had your vitamins figured out, science throws us a curveball. New research from Texas A&M University is challenging everything we thought we knew about folate (that’s vitamin ...

When you think about nutrition, folate may not be the first nutrient that comes to mind. However, this B vitamin is crucial for your health. Folate is required for DNA synthesis and forming new cells, ...

Although they number from 1 (thiamine) to 12 (cobalamin), there are eight B vitamins—don't bother seeking numbers 4, 8, 10, or 11. The rest are all facilitators of the nervous system and tend to work ...