These authors evaluated the GRI conjugate according to its capacity to replace both prandial and basal needs using laboratory-based assessments and preclinical mouse and mini-pig models (Figure 1).

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Type 1 diabetes (T1D) is an autoimmune condition where the immune system destroys insulin-producing β-cells in the pancreas. Yet, not all patients lose insulin function at the same pace. Understanding ...

New research indicates that an acute exercise session may improve isolated muscle insulin resistance in carriers of a TBC1D4 nonsense mutation, a variant linked to hyperinsulinaemia and elevated type ...

Genetic engineering is moving from the lab bench into clinics, farms, and even family planning decisions, promising to change how we prevent disease, age, and define human potential. The same tools ...

Our body controls the levels of sugar in our blood with a hormone called insulin, which is made by beta cells in the pancreas. In type 1 diabetes, the immune system erroneously attacks those beta ...

In a recent study published in the journal Scientific Reports, researchers analyzed whole-exome genetic data from more than 2,000 Ashkenazi Jewish centenarians and their relatives to investigate ...

Researchers identify genetic markers that predict the rate of β-cell failure in type 1 diabetes, facilitating earlier, personalized care strategies Type 1 diabetes (T1D) is an autoimmune condition ...