Placing UV detectors far away from a chromatographic column can be problematic. The increased extra column volume can cause band broadening, reducing the efficiency of a separation. Also, experiments ...

Natural products and their derivatives continue to have an important role as a resource for various pharmaceuticals and biologically active substances. Some synthesized drugs were inspired by the ...

Ultra-High Performance Liquid Chromatography (U-HPLC) is an advanced form of liquid chromatography used to separate components in complex mixtures. Identification and quantification of the separated ...

Analysts interested in organic molecules like dissolved organic matter or pharmaceuticals should consider quantifying organic molecules with the High Performance Liquid Chromatography (HPLC) ...

Extracts of luo han kuo fruit used as sweeteners were acknowledged as Generally Recognized as Safe (GRAS) based on a GRAS submission to the U.S. FDA in January of 2010.2 Typical reversed-phase ...

The term liquid chromatography (LC) refers to a class of physicochemical methods which are used to separate and quantify compounds in a sample. LC is made up of a liquid mobile phase, which carries ...

This case study highlights analytical instrumentation and techniques that were used to identify an unknown impurity detected during routine release testing of a topical gel drug product. It is not ...