Helicases are enzymes that unwind DNA and RNA. They’re central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs. Now, new ...

Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections - and, alas, extraordinarily difficult to target with drugs. Now, new ...

CHAMPAIGN, Ill. – Thanks to a single-molecule imaging technique developed by a University of Illinois professor, researchers have revealed the mechanisms of an important DNA-regulating enzyme.

New research shows that the nuclease domain of the E. coli RecBCD helicase plays a key role in regulating DNA binding and the extent of base pair melting during double-strand break repair. Deleting ...

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works. Subscribe to our newsletter for the latest sci-tech news updates. The discovery ...

Enzymes, which are crucial to controlling how cells replicate in the human body, could be the very ingredient that encourages DNA to spontaneously mutate -- causing potentially permanent genetic ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for coronavirus disease 2019 (COVID-19), continues to cause mayhem all over the world. Because of this, the scientific ...

Since the 1990s, nanopores have been used for sequencing strands of DNA. A voltage is applied across the nanopore, which is embedded in a thin lipid membrane, causing a stretch of DNA to thread ...

Staphylococcus aureus—also known as "golden staph"—has the ability to develop in highly variable environmental conditions (on the skin, in the nose, on sterile surfaces, and so forth). Its great ...