Hospitalized children who receive hypotonic maintenance intravenous (IV) fluids are at higher risk of developing hyponatremia than those receiving isotonic IV fluids, according to a recent ...

In general, 0.25% saline is rarely used as a hydration fluid by itself. Because of the tonicity gradient, free water would enter the red blood cells, causing them to swell. This could lead to cell ...

Hypotonic fluid administration has been the standard of care for maintenance fluid therapy in acutely ill children, but this approach is associated with hospital-acquired hyponatraemia and ...

We examined the underlying mechanisms of whether hyponatremia could be induced by hypotonic solution administration after the postoperative invasive phase (POIP). Hyponatremia frequencies on POD 3 ...

Statement 1 Term neonates, children and young people receiving intravenous (IV) fluid therapy have their plasma electrolyte concentrations and blood glucose measured when starting IV fluids and then ...

Critically ill patients admitted to intensive care settings may need to be administered intravenous fluids – for example, to restore their blood pressure or replace lost blood. A crucial question ...

Every day, children and young people are prescribed IV fluid therapy for a variety of reasons. However, there is little evidence on IV fluids in children and young people, and the limited evidence ...