Introduction Hypoxia is a hallmark of solid tumours and drives radioresistance, yet no hypoxia biomarkers are used clinically. We explored nanoproteomics to identify ...

As an emerging concept, panvascular diseases encompass a group of cardiovascular disorders characterized mainly by atherosclerosis, involving crucial organs such as the heart, brain, kidneys, and ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. On February 12, the FDA accepted its first new drug ...

A blind spot in modern ophthalmology may finally have a name. In a sweeping review published in the Journal of Translational ...

A recent study posted to the bioRxiv* preprint server assessed the role of hypoxia-inducible factors (HIF) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, respiratory ...

Hypoxia-inducible factor is a type of transcription factor that responds to the changing level of oxygen supply to the cell. The discovery of how it functions in the body to allow cells to respond to ...

•Hypoxia-inducible factors (HIFs) regulate genes involved in angiogenesis, invasion and metabolic reprogramming, essential for cancer progression. •HIF-1α triggers metabolic changes, including the ...

Clinical performance of Signatera Genome assay in a cohort of patients (pts) with solid tumors. Pooled mutation frequencies for all considered genes in different cancer types.

This study is led by Prof. Junbo Ge (Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases), Prof. Hua Li (Department of Cardiology, Zhongshan ...