Our EM-iSCAT microscopy supports two operation modes: the whole-cell mode and the single-channel mode. In the former, cellular electrophysiological analysis was achieved by tracking overall changes in ...

In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of Biophysics of the Chinese Academy of Sciences has developed a ...

Fluorescence microscopy techniques are powerful tools for probing very small signals and revealing three-dimensional (3D) structural and functional properties of biological samples with high ...

Figure | Working principle of Interferometric Image Scanning Microscopy (iISM). (a) Schematic of the iISM microscope and interferometric PSF detection. (b) iISM with adaptive pixel-reassignment (APR) ...

Single-molecule super-resolution microscopy allows pinpointing individual molecular positions in cells with nanometer precision. However, achieving molecular resolution through tissues is often ...

Image by the US National Institutes of Health, CC 3.0 A new dual-light microscope lets researchers observe micro- and nanoscale activity inside living cells without using dyes. The system, from the ...

A research team led by Prof. Liu Xianwei from the Department of Environmental Science and Engineering of University of Science and Technology of China (USTC) of the Chinese Academy of Science (CAS) ...

Evanescent scattering microscopy is a label-free optical imaging technology that uses evanescent fields and interferometric light scattering to detect and characterize single biomolecules in real time ...

Researchers have unveiled a groundbreaking approach to label-free visualization of intracellular cargo trafficking in living cells, achieving high-speed and limitless observation capabilities. By ...

Image by the US National Institutes of Health, CC 3.0 Image by the US National Institutes of Health, CC 3.0 A new dual-light microscope lets researchers observe micro- and nanoscale activity inside ...