In contrast to normal prostatic epithelial cells, which are not able to regenerate and grow in an androgen-deprived state, prostate cancer cells almost always manage to acquire an androgen-independent ...

An analysis of four randomized controlled studies in patients with advanced prostate cancer who had received early vs. deferred ADT as primary therapy showed that early androgen suppression ...

Receiving androgen-deprivation therapy (ADT) on an intermittent basis does not appear to be a wise choice for men with metastatic hormone-sensitive prostate cancer, according to a landmark trial ...