A team of researchers has found a quicker and more efficient way to create nucleoside analogs, a type of small molecule that can be used in treatments for everything from cancer to viral diseases.
Charlie's parents wanted to take the 11-month-old baby to the US against the wishes of doctors in a bid to save his life THE world was touched by the case of Charlie Gard as his parents fought a ...
Nucleoside derivatives have important therapeutic activity in chronic lymphocytic leukaemia (CLL). Experimental evidence indicates that in CLL cells most of these drugs induce apoptosis ex vivo, ...
Acyclic nucleoside phosphonates (ANPs) represent a vital class of compounds with significant applications in antiviral and antiparasitic therapy. Characterised by a non-hydrolyzable phosphonate group, ...
Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics. Several researchers at the University of ...
The coronavirus disease 2019 (COVID-19) pandemic has infected around 225 million people and claimed more than 4.64 million lives worldwide. This pandemic is caused by severe acute respiratory syndrome ...
Combination antiretroviral therapy (ART) has transformed HIV-1 infection into a chronic condition with near-normal life expectancy. For more than two decades, the standard regimen has been a ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), identified as the causative agent of the COVID-19 (coronavirus disease 2019) pandemic, was first detected in Wuhan, China late December ...
Acute lymphoblastic leukemia is the most common type of childhood leukemia, with about 5,000 children diagnosed in the U.S. each year. Now researchers have synthesized a nonnatural deoxynucleoside ...
Cardiomyopathy with Mitochondrial Damage Associated with Nucleoside Reverse-Transcriptase Inhibitors
In July 2000, a 58-year-old man infected with the human immunodeficiency virus (HIV) began treatment with highly active antiretroviral therapy, which initially consisted of zidovudine, lamivudine, and ...
A joint research by Chinese scientists has recently found that the oral nucleoside drug VV116, approved for the treatment of COVID-19, shows significant antiviral activity against Nipah virus, ...
Obeldesivir (GS-5245), a novel investigational small molecule oral antiviral, represents a new tool in the ongoing effort to prepare for future pandemics. Obeldesivir (GS-5245), a novel ...
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