Nature

An approach for cutting large and complex pedigrees for linkage analysis

Utilizing large pedigrees in linkage analysis is a computationally challenging task. The pedigree size limits applicability of the Lander–Green–Kruglyak algorithm for linkage analysis. A common ...
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Nature Methods Paper Leverages PacBio Sequencing Technology to Develop the Platinum Pedigree Benchmark, a New Standard for Accurate Characterization of Variation in the Human ...

MENLO PARK, Calif., Aug. 04, 2025 (GLOBE NEWSWIRE) -- PacBio (PACB), a leading provider of high-quality, highly accurate sequencing platforms, today announced the results of a study published in ...
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Mutation rates in whales are much higher than previously reported

An international team of marine scientists, led by the University of Groningen in the Netherlands and the Center for Coastal Studies in the USA, has studied the DNA of family groups from four ...
JSTOR Daily

Estimating Genetic Correlations in Natural Populations in the Absence of Pedigree Information: Accuracy and Precision of the Lynch Method

Usually, genetic correlations are estimated from breeding designs in the laboratory or greenhouse. However, estimates of the genetic correlation for natural populations are lacking, mostly because ...
JSTOR Daily

An Application of the Latent p Value Method to Assess Linkage in Asthma Pedigrees

This is a preview. Log in through your library . Abstract Objective: The latent p value is a recently proposed empirical method for assessing evidence against a null hypothesis in a stochastic system ...
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Nature Methods Paper Leverages PacBio Sequencing Technology To Develop the Platinum Pedigree Benchmark

PacBio (NASDAQ: PACB), announced the results of a study published in Nature Methods describing a new, comprehensive truth-set of genomic variation which characterizes simple and complex variation.
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Golden Goose Award Announces 2023 Awardees for Discoveries in DNA Sequencing Technique, A Bacteria-Inspired Method that Saves Crops and Chicken Pedigree Lines (IMAGE)

Golden Goose Award Announces 2023 Awardees for Discoveries in DNA Sequencing Technique, A Bacteria-Inspired Method that Saves Crops and Chicken Pedigree Lines (IMAGE) American Association for the ...