One of the biggest challenges in cancer research is understanding why some tumor cells become especially aggressive, invasive and resistant to treatment. Scientists have increasingly linked these ...

(A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage.(B) After treatment with the anti-cancer drug cisplatin, ...

Cancer cell DNA doubling — when cells accidentally duplicate all chromosomes without dividing — now has a new risk factor: ...

Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies. Polyploidy often occurs in human diseases and cancers, and its ...