For many men diagnosed with advanced prostate cancer, one of the biggest concerns is how long treatment will continue working ...

Radiotherapy is a common therapeutic modality for the treatment of human epithelial tumors, including those of prostate origin [1]. Despite considerable improvements in delivering the radiation dose ...

A transcriptome analysis of castration resistant prostate cancer metastases in a prospective cohort study reveals high expression of AKT pathway genes predictive of long term response to abiraterone ...

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer This was a prospective, cross-sectional, ...

The PARP inhibitor Lynparza improves survival and delays disease progression in men with metastatic castration-resistant prostate cancer that expresses certain gene mutations inhibiting DNA repair, a ...

Prostate-specific membrane antigen radioligand therapy (PSMA-RLT) is a novel treatment for castration-resistant prostate cancer (mCRPC). While the majority of patients responds to PSMA-RLT, with 10–15 ...

"Men with these known variants should be counseled on the increased risk of prostate cancer, and I would recommend that they undergo regular PSA screening…Of course there are many other factors that ...

Identification of variants influences treatment decisions. Inhibitors of the poly-ADP-ribose polymerase (PARP) system, a pathway for repairing single-stranded DNA breaks, are recommended for tumors ...

Medically reviewed by Jamin Brahmbhatt, MD Key Takeaways Stage 4 prostate cancer is advanced and has spread beyond the prostate.Hormone therapy is often used to treat stage 4 prostate cancer by ...

The prostate is a small gland that plays an important role in male reproductive anatomy. Prostate problems can have a range of causes, including prostatitis, benign prostatic hyperplasia, and prostate ...