Eukaryotic cells rely on an integrated network of surveillance pathways to maintain protein homeostasis, ensuring that nascent chains fold correctly, damaged polypeptides are recognised and misfolded ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mitochondrial quality control (MQC) mechanisms - including biogenesis, dynamics, mitophagy, proteostasis, ...

Researchers at Pennington Biomedical Research Center have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin ...

Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, ...

Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that increase cell stress and may contribute to diseases such as cancer and ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, ...

Images of human cells at different stages of mitosis. Chromosomes are colored cyan, spindle microtubules in red and spindle poles are yellow. Each day, hundreds of billions of cells in our body cycle ...