RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...
Medical Xpress

RNA-seq outperforms DNA methods in detecting actionable cancer mutations

RNA-seq succeeded across all tumor types and tissue formats, including degraded FFPE samples. Researchers conclude that targeted RNA-seq can serve as a stand-alone molecular diagnostic with high yield ...
Baylor College of Medicine

Baylor researchers develop and validate clinical diagnostic RNA sequencing test

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...
EurekAlert!

New review decodes transcriptomics: bulk vs. single-cell RNA sequencing

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
EurekAlert!

Singapore scientists unveil one of world’s largest long-read RNA sequencing datasets to advance disease research

SG-NEx provides an open-access resource for the global research community, accelerating biomarker discovery and precision medicine through: Singapore – A team of scientists led by the A*STAR Genome ...
Baylor College of Medicine

Researchers show benefit of ultra-deep RNA sequencing in Mendelian disorder diagnostics

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...
GEN

Plasmidsaurus Launches Ultrafast RNA-Seq Service

Plasmidsaurus has launched a new RNA-Seq service for Illumina short read applications, bringing the same approach they use for plasmid sequencing to gene expression analysis. Attendees at this week’s ...