Scleroderma is an autoimmune, rheumatic, and chronic disease that affects the body by hardening connective tissue, according to the Johns Hopkins Scleroderma Center. For the almost 500,000 people in ...

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Scleroderma is a range of disorders in which the skin and connective tissues tighten and harden. It is a long-term, progressive disease. This means it gradually gets worse. Share on Pinterest ...

The finding of collagenous encapsulation of Brunner's glands and pathological changes in the muscularis mucosae in a duodenal biopsy from a patient with severe progressive systemic sclerosis prompted ...

Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the appearance and texture of your skin and affect other organs. Systemic sclerosis (SS) is an autoimmune ...