The molecular identity of the human mitochondrial calcium uniporter has now been elucidated using integrative genomics. The mammalian uniporter is a protein complex consisting of the inner ...

While calcium's importance for our bones and teeth is well known, its role in neurons -- in particular, its effects on processes such as learning and memory -- has been less well defined. A new study ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

Mitochondria are key integrators of cellular calcium (Ca2+) signaling and energy metabolism. Early studies demonstrated that isolated mitochondria could buffer huge amounts of Ca2+ via a highly ...

Mitochondria -- the energy-generating powerhouses of cells -- are also a site for oxidative stress and cellular calcium regulation. The latter two functions have long been suspected of being linked ...

Knowing how ATP is produced by the cell’s energy storehouse – the mitochondria -- is important for understanding a cell’s normal state, as well as what happens when things go wrong, for example in ...

JUPITER, FL - August 25, 2016 - While calcium's importance for our bones and teeth is well known, its role in neurons--in particular, its effects on processes such as learning and memory--has been ...