ZFNs are artificial restriction enzymes containing a zinc-finger array (ZFA) engineered to recognize different DNA sequences, fused through a flexible linker to the nuclease domain of FokI (ref. 1).

Many fighters dream of stepping into the UFC octagon, but only the elite make it to the biggest stage in MMA. At the UFC 308 press conference, Tajikistani fighter Dorobsho Nabotov made waves by ...

If you're an investor who's heard of zinc-finger proteins and gene editing but you aren't sure what it all means, this can help answer your questions. There are 350 million people worldwide with rare ...

Targeted genetic engineering in many important model systems and in human tissue culture cells has historically been challenging. This has changed dramatically over the past 5 years with the ...

The determination of complete genome sequences for a wide variety of experimental organisms established a first step in the search for an in-depth understanding of the complex genetic functions that ...

Applications of ZFN technology in biopharmaceutical cell-line engineering. Genome editing has played a prominent role in the development of Chinese Hamster Ovary (CHO) cells for biopharmaceutical ...

Horizon Discovery (Horizon) has announced that it has entered into a non-exclusive license agreement with Sigma-Aldrich (Sigma) for use of their CompoZr ® zinc finger nuclease (ZFN) technology. The ...

There are 350 million people worldwide with rare diseases and about 80% of those diseases, including cystic fibrosis, are caused by faulty genes. In most cases, genetic disorders lack effective ...

There are 350 million people worldwide with rare diseases and about 80% of those diseases, including cystic fibrosis, are caused by faulty genes. In most cases, genetic disorders lack effective ...