America's relationship with its biggest Middle East adversary has changed dramatically over the decades. Investors are weighing a NYT report that Iran has indirectly approached the US to discuss terms for ending the conflict. Markets are reacting to a lack of clarity and shifting expectations in the first days of a chaotic conflict.

Secretary of War Pete Hegseth declared Wednesday that Iran “cannot outlast” the U.S. in a conflict as its military has been decimated as a result of Operation Epic Fury, which is now in its fifth day.

President Donald Trump said the objective is to defend the American people by eliminating imminent threats from the Iranian regime. He said Iran has continued to develop nuclear weapons.

Iran doesn’t want to talk. It doesn’t want to parley. And it’s not sitting down with President Donald Trump. Here's what may be next in the Iran war.

Israel decided days after Hamas’ Oct. 7 attack to target Iran’s Supreme Leader Ali Khamenei, while detailed planning came later, USA TODAY learned.

Israel and the U.S. bombed Iranian missile sites and targeted its navy, claiming to have destroyed its headquarters and multiple warships.

DUBAI, United Arab Emirates (AP) — Iran launched a new wave of attacks Thursday morning at Israeli and American bases and threatened that the United States would “bitterly regret” torpedoing an Iranian warship in the Indian Ocean while Israel said it had begun a “large-scale” attack on Tehran.

Gulf governments emphasize sovereignty and civilian protection as Iran-aligned actors frame the confrontation as external aggression As Iranian missiles and drones crossed multiple airspaces and the