However, it turned out that Dicer does not always operate as scientists expect. The enzyme primarily functions like a molecular ruler, consistently measuring a length of 22 nucleotides. During the ...
How an enzyme, appropriately named DICER, cuts double-stranded RNA to produce short sections of RNA that regulate genes has been revealed. Small snippets of RNAs can turn off genes, stopping them from ...
Diana Maltseva, at el. Incautious design of shRNAs for stable overexpression of miRNAs could result in generation of undesired isomiRs, Biochimica et Biophysica Acta (BBA) — Gene Regulatory Mechanisms ...