Outcome-adaptive randomization is one of the possible elements of an adaptive trial design in which the ratio of patients randomly assigned to the experimental treatment arm versus the control ...

Sound experimental design is of vital importance when conducting any scientific experiment. Choices made at the design stage have the potential to drastically impact the results of any study. A strong ...

Introductory quantitative skills required to conduct experimental research and analyze resulting data. Principles of measurement, modeling of experimental data, and statistical design of experiments.

The genetic and clinical heterogeneity of breast cancer makes the identification of effective therapies challenging. We designed I-SPY 2, a phase 2, multicenter, adaptively randomized trial to screen ...

Methods for designing and analyzing industrial experiments. Blocking; randomization; multiple regression; factorial and fractional factorial experiments; response surface methodology; Taguchi’s robust ...

Educational research often studies subjects that are in naturally clustered groups of classrooms or schools. When designing a randomized experiment to evaluate an intervention directed at teachers, ...

This is a preview. Log in through your library . Abstract Well defined methods for comparing mean polynomial growth curves exist when subjects are measured at identical times, modeled with polynomials ...

In this module, we will introduce the basic conceptual framework for experimental design and define the models that will allow us to answer meaningful questions about the differences between group ...