Uremic encephalopathy: Video & Meaning | Osmosis

Aazer Nawab on Instagram: "Because giving glucose first can precipitate Wernicke’s encephalopathy. Now simple logic: •Chronic alcoholics are thiamine (Vitamin B1) deficient (poor diet + decreased absorption + impaired storage in liver) •Thiamine is a cofactor in carbohydrate metabolism (pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, transketolase) •When you suddenly give IV dextrose, metabolism increases → brain needs more thiamine → already deficient patient collapses metabolically → ac

Prions (Spongiform encephalopathy): Video, Causes, & Meaning | Osmosis

Bovine spongiform encephalopathy in biology

Medicinema on Instagram: "Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease CJD appears to be caused by an abnormal infectious protein called a prion These prions accumulate at high levels in the brain and cause irreversible damage to nerve cells Symptoms reported: > Memory loss. > Impaired thinking. > Blurry vision or blindness. > Insomnia. > Trouble speaking. > Trouble swallowi